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UKPDS Outcomes Model v2.2

For non-commercial use

Please note that to help cover the cost of the ongoing development of the software and related research, there is a need to charge all users (commercial/ academic/ public sector) a license fee for use of the simulation model. However, the license fees for the use of UKPDS OM software can be waived for research where there is no funding through either industry or research grants, for example PhD projects. Feel free to reach out for more information on the licensing arrangements and pricing as we are able to supply quotes for budgeting of future projects.                    

Use the non academic version of the request form if you do not qualify UKPDS Outcomes Model ( 

UKPDS OM 2.1 FREE Launch webinar - click here to watch

Hear from the UKPDS OM developers from Oxford University and learn more about the model, including: 
  • An introduction to the model and the latest features
  • A demonstration of the UKPDS Outcomes Model version 2.1
  • Hints and tips on how to get the most out of the model

The UKPDS Outcomes Model is a computer simulation model based on patient-level data collected as part of the United Kingdom Prospective Diabetes Study, which has been extended to include 30 years of follow-up data. 

Designed to predict clinical events, life expectancy, costs and quality of life over a lifetime for populations with type 2 diabetes, based on a wide variety of input data, including knowledge of previous clinical events for individuals, and can take into account changes in risk factor levels over time.  

The model has been widely implemented around the globe:

UKPDS user map

The software can facilitate economic evaluations by estimating changes in outcomes such as life expectancy and quality adjusted life expectancy, and costs for each member of a given population when risk factors such as blood glucose level, blood pressure, lipid levels and smoking status are changed. 

The newly launched version 2.1 includes greater usability and extended features including:
  • Comparison of up to 25 treatment groups simultaneously
  • New outputs showing convergence, and costs and disutilities split by event
  • Generation of outputs for up to five user defined composite outcomes
  • Major speed improvements. Up to 124 processors can now be utilised
  • Disabling selected output sheets to increase speed
  • Disk space optimisation for larger datasets

Applications include: 
  • Population-based health economic analyses 
  • Health service planning 
  • Estimating life expectancy and health events for improving accuracy of insurance and actuary models. 
  • Calculating expected event rates for sample size calculations in clinical trial design.  

The UKPDS Outcomes Model has been used in a range of research, clinical and commercial applications worldwide, as well as by NICE, and can operate on Windows and Mac OS X platforms. It uses Microsoft Excel workbooks to store input and output data which can be queued for processing in turn by the OM2 Controller Application which runs the model. The model is available as a standalone desktop application for Windows or Mac, and the download also includes a user manual.

Published papers, conference abstracts and more information about the UKPDS Outcomes Model is available on the Diabetes Trial Unit website                          

Please contact Karl Dickinson ( should you have any questions.             

For technical queries, please contact the Outcomes Model Team (

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